CGCF Price Schedule
Service Request Form
- Please contact us when you plan the screening project. We’ll discuss assay adaptation for your target of interest, necessary controls, screening procedures and estimated cost.
- Screening experiments must be scheduled in advance. Instrument time and library compounds must be reserved at least a week in advance. Cancellations should be made at least 24 hours in advance.
- An account number should be provided and a service request form (see above links) should be filled out prior to any service.
- Only the staff members of the core facility are permitted to handle the compound libraries, and will perform compound transfer from the storage plates to the pre-assay plates. Screeners perform their own assays and provide their own supplies including assay plates (please consult us for the type of plates to use), all reagents and other consumables such as pipette tips, solution containers, etc. Training in operating liquid handling equipment and plate reader will be provided by the staff members.
- Screeners should re-order compounds for the secondary screen and all other follow-up experiments. For more information, please contact us.
- The core facility stores the original data on their hard drives during the screening period. Data analysis on those data will also be provided by the core. A database is to be built in the core to manage all data. Screeners may transfer some of their data to their own devices for record and further analysis.
- The Chemical Genomics Core Facility is not for profit. We provide services concerning small molecule screening to the research community within the state. Screeners will provide personnel to conduct the screen, as well as their own reagents and consumables. In order to sustain the operation of the facility, a cost recovery measure was established with a price schedule in effect starting July 17, 2007.
- Confidentiality: All the data generated from the services will be accessible to the investigators only. These data will not be presented in anyway without permission from the investigators. The only information that the core will disclose in its reports and other presentations would be the title of the project and the type of assay used for HTS.
- Conflict Resolution: The Core Director will discuss all issues with the investigator and help to redesign the experimental protocol. Should other issues (such as charge disputes, authorship, and conflict of interest) arise, the Advisory Committee will assist in conflict resolution.
- Cost Recovery: A charge back is applied to all users. This charge offsets, only in part, the substantial costs associated with maintaining equipment and library compounds. Details of the charges levied on work and compound usage. A guideline of fee structure is available by contacting the Core director.
- Payment Policies: All users of the Core are expected to pay for the services provided by the core. An IU account number or a purchase order number (PO#) should be provided at the beginning of the service. A full payment is expected if screening data is obtained regardless whether or not it represents the result expected by the investigator. If a screening project is aborted due to the nature of the assay, which should be provided by the investigator, a partial payment is expected to recover the material costs and equipment depreciation. The figure of the payment is determined by the Core Director.
- Prioritization: A priority will be given to the investigator who is affiliated with Cancer Center and the Department of Biochemistry and Molecular Biology. All other services are based on first-come-first-serve policy.
- Publication Policy: Inclusion of the core members as authors in publications should be considered when and only when their contribution exceeds technical expertise and support. The re-charge mechanism does not preclude or replace authorship. If substantial intellectual contributions are required in assay development and implementation, and/or manuscript writing and data interpretation are requested, co-authorship should be granted to the involved core personnel.
- Acknowledgement: We kindly request that any work that results in publications from the use of the core should appropriately acknowledge the Chemical Genomics Core Facility at Indiana University and Indiana Clinical and Translational Sciences Institute (CTSI). Please also keep us informed of status of grants in which the use of the CGCF is proposed.